Medichem - II mcqs
A. Muscarnic M1 receptor agonist
B. Non selective β- receptor antagonist
C. Selective β1agonist
D. Non selective dopaminergic antagonist
2. An acrylolyl moiety containing diuretic is
A. Indacrinone
B. Ethacrynic acid
C. Torsemide
D. Canrenone
3. The substitution of an aryl group which increase the electron density of carbonyl oxygen,
in the structure of LA results in
A. Increased relative toxicity
B. Decreased relative toxicity
C. Increased local anaesthetics activity
D. Decreased local anaesthetic activity
4. Drug receptor site for Sulfonylurea is
A. muscarinic receptor
B. calcium channel
C. potassium channel
D. beta adrenergic receptor
5. Captopril, Lisinopril and Enalapril are
A. ACE inhibitors
B. Beta blockers
C. Alpha2 antagonists
D. None of the above
6. Chemically, mechlorethamine is
A. Bis(2-chloroethyl)(methyl)amine
B. Bis(2-chloromethyl)(ethyl)amine
C. Bis(2-chloroethyl)(propyl)amine
D. Bis(2-chloropropyl)(methyl)amine
7. Which one of the following local anesthetics belongs to the ester group?
A. Procaine
B. Bupivacaine
C. Lignocaine
D. Mepivacaine
8. The cisplatin can be used as
A. Calcium channel blocker
B. Antiarrhythemic drug
C. Antineoplastic cytotoxicity drug
D. Immuosuppressive agent
9. Which one of the following is essential for optimum activity of calcium channel blockers?
A. Phenyl substitution at 3rd position
B. Phenyl substitution at 4th position
C. Phenyl substitution at 5th position
D. Phenyl substitution at 6th position
10. Therapeutic use of amyl nitrite is
A. Treatment of angina pectoris
B. Treatment of methemoglobinemia
C. Treatment of syncope
D. None of the above
11. Steroid can used to
A. Stimulate muscle growth
B. Cause eye site
C. To increase intelligent
D. All of the above
12. The basic PPI pharmacophore is
A. 2-pyridyl methylsulfinylbenzimidazole
B. 2-pyridyl ethylsulfinylbenzimidazole
C. 1-pyridyl methylsulfinylbenzimidazole
D. 1-pyridyl ethylsulfinylbenzimidazole
13. The drug Promethazine is mainly used for treatment of?
A. Nausea
B. Motion sickness
C. Tension
D. All of the above
14. The term is used to indicate the ability of a cancer to invade other parts of the body and to
produce secondary tumours is
A. Carcinogenesis
B. Apoptosis
C. Metastasis
D. Mutagenesis
15. Busulfan acts by...
A. Fragmentation of DNA
B. Mispairing of nucleotides
C. Separation of DNA strands
D. All of the above
16. Activity of 6-Mercaptopurine can be increased by
A. Hydrophilic substitution at 6th position
B. Increase in the alkyl chain length
C. Any substitution at 2nd position
D. Decrease in the alkyl chain length
17. The starting material for synthesis of Nitroglycerine is
A. Trinitroglyceraldehyde
B. Glyceraldehyde
C. Trinitroglycerol
D. Glycerol