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| Medichem 2 most imp que 2 marks Questions 1. Discuss structure and write uses of diphenylamine hydrochloride. 2.write mechanism of action of methotrexate. 3. Draw structure and mechanism of action of verapamil 4. Draw the structure and uses of loop diuretics drugs. 5. Discuss mechanism of action and draw structure of sildenafil. 6. Write short note on digitoxin. 7. Discuss metabolic pathway of insulin. 8. Define 3D QSAR. 10 Marks Questions 1. Write the SAR and mechanisms of action of H2 receptor antagonists. 2. Write the synthesis and mechanisms of action of Acetazolamide. 3. Classify anti anginal drugs and give synthesis and SAR of isosorbide dinitrite. 5 Marks Questions 1. Give the SAR and synthesis of disopyramide phosphate 2. Classify anticoagulants. Write the SAR and synthesis of Warfarin. 3. Classify antithyroid drugs and write a detailed note on Propylthiouracil. 4. Classify sulphonylurease and bigaunides derivatives. Write SAR of tolbutamide. 5. Write the structural classification of local anesthetic, write the mechanism of benzocaine. 6. Write the SAR and mechanism of meclorethamine. 7. Write the SAR and mechanism of action meclorethamine. 8. Write the structural classification of oral contraceptive |
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V sem